SCHEMBL3805652

SCHEMBL3805652

COc1cc(OC)c2c(c1)O[C@H](c1ccc(O)c(O)c1)[C@H](OC)C2

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.59
▸ MAPK1 P28482 1/20 0.59
▸ ABCB1 P08183 15/20 0.53
▸ MMP2 P08253 3/20 0.52
▸ MMP14 P50281 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL862189 0.93 CYP3A4 (0.59) CYP3A4MAPK1ABCB1
SCHEMBL5359695 0.93 CYP3A4 (0.59) CYP3A4MAPK1ABCB1
SCHEMBL862107 0.91 MMP2 (0.59) CYP3A4MAPK1MMP2MMP14
SCHEMBL862370 0.89 MMP2 (0.61) CYP3A4MAPK1MMP2MMP14
SCHEMBL25246785 0.87 CYP3A4 (0.78) CYP3A4MAPK1ABCB1
SCHEMBL862416 0.87 CYP3A4 (0.78) CYP3A4MAPK1ABCB1
SCHEMBL862428 0.82 MMP2 (0.53) MMP2MMP14
SCHEMBL1973504 0.81 CYP3A4 (0.80) CYP3A4MAPK1ABCB1
Meciadanol SCHEMBL790768 0.81 BACE1 (0.68) CYP3A4MAPK1MMP2MMP14
Meciadanol SCHEMBL790769 0.81 BACE1 (0.68) CYP3A4MAPK1MMP2MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210015964-A1 METHOD OF FORMING AND USING A HEMOSTATIC HYDROCOLLOID UNITED HEALTH PRODUCTS INC (US) 2021-01-21 — — US disclosed
US-20140046277-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC. 2014-02-13 — — US disclosed
US-8557874-B2 Hemostatic material EPIC WOUND CARE, INC. (US) 2013-10-15 — — US disclosed
WO-2012142317-A1 FAST-CLOTTING WOUND DRESSINGS GAMMA THERAPEUTICS, INC (US) 2012-10-18 — — WO disclosed
WO-2009070684-A2 HEMOSTATIC MATERIAL BAGGETT RICHARD W (US) 2009-06-04 — — WO disclosed
US-20090136562-A1 Hemostatic Material UNITED ECOENERGY CORP. 2009-05-28 — — US disclosed
WO-2009002768-A2 LIQUID BANDAGE MEDSPRING GROUP, INC. (US) 2008-12-31 — — WO disclosed
EP-1638491-A4 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT UNIV LOMA LINDA MED (US) 2008-05-28 — — EP disclosed
US-20080031929-A1 LIQUID BANDAGE MEDSPRING GROUP, INC. 2008-02-07 — — US disclosed
US-20070026052-A1 Hemostatic material UNITED ECOENERGY CORP. 2007-02-01 — — US disclosed
EP-1638491-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT Loma Linda University Medical Center (US) 2006-03-29 — — EP disclosed
US-20050123588-A1 Deployable multifunctional hemostatic agent LOMA LINDA UNIVERSITY MEDICAL CENTER 2005-06-09 — — US disclosed
WO-2005002510-A2 DEPLOYABLE MULTIFUNCTIONAL HEMOSTATIC AGENT LOMA LINDA UNIVERSITY MEDICAL CENTER (US) 2005-01-13 — — WO disclosed
US-20030044380-A1 Adhesive including medicament LOMA LINDA UNIVERSITY 2003-03-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044380-A1 Adhesive including medicament ICAM1, VCAM1, EPCAM CYP3A4 4815/4885MAPK1 4331/4885ABCB1 520/4885
US-20080031929-A1 LIQUID BANDAGE FGB, F2, F8 CYP3A4 3316/4885MAPK1 4222/4885ABCB1 3964/4885
US-20050123588-A1 Deployable multifunctional hemostatic agent FGB, CHIT1, CHIA CYP3A4 3864/4885MAPK1 4055/4885ABCB1 4815/4885
US-20070026052-A1 Hemostatic material F2, F8, F3 CYP3A4 2679/4885MAPK1 4199/4885ABCB1 4279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback