Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.96 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TYMS | P04818 | 1/20 | 0.60 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.59 |
| ▸ | TNKS | O95271 | 2/20 | 0.58 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL47352 | 0.98 | PARP1 (1.00) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL8621956 | 0.96 | PARP1 (0.96) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL21968820 | 0.90 | PARP1 (0.83) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL11546086 | 0.78 | KDM4E (1.00) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL6695759 | 0.78 | TNKS2 (0.81) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL29535139 | 0.76 | KDM4E (0.66) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL7263029 | 0.76 | KDM4E (0.66) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL17460813 | 0.76 | PARP1 (0.62) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL30704851 | 0.76 | PARP1 (0.62) | PARP1TNKS2KDM4EALDH1A1MAPT | |
| SCHEMBL5199045 | 0.75 | TNKS2 (0.62) | PARP1TNKS2KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830909-A | DIETETICS | AMERICAN CYANAMID COMPANY (US) | 1998-11-03 | — | — | US | claimed |
| US-5830909-A | DIETETICS | AMERICAN CYANAMID COMPANY (US) | 1998-11-03 | — | — | US | disclosed |