SCHEMBL8622137

SCHEMBL8622137

CS(=O)(=O)c1ccccc1C(=O)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
BCAT2 O15382 1/20 0.60
GAA P10253 3/20 0.58
HPGD P15428 3/20 0.58
LMNA P02545 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TP53 P04637 1/20 0.57
GLA P06280 1/20 0.57
APEX1 P27695 1/20 0.57
METAP2 P50579 1/20 0.56
CHRNB2 P17787 1/20 0.56
CHRNB4 P30926 1/20 0.56
CHRNA3 P32297 1/20 0.56
CHRNA4 P43681 1/20 0.56
ALDH1A1 P00352 2/20 0.56
HSD17B10 Q99714 2/20 0.56
KDM4E B2RXH2 2/20 0.55
POLB P06746 1/20 0.55
TSHR P16473 1/20 0.55
RECQL P46063 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5357492 0.83 CA4 (0.70) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL11436373 0.83 KMT2A (0.59) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL11435087 0.83 KMT2A (0.59) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL31680569 0.81 KMT2A (0.89) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL11901003 0.81 KMT2A (0.89) KMT2AGAAHPGDLMNAL3MBTL1
Hydrochloric Acid SCHEMBL18050032 0.81 BCAT2 (0.59) KMT2ABCAT2LMNAL3MBTL1TSHR
SCHEMBL2741011 0.81 KMT2A (0.56) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL11435085 0.81 KMT2A (0.56) KMT2AGAAHPGDLMNAL3MBTL1
SCHEMBL7984802 0.80 BCAT2 (0.67) KMT2ABCAT2GAALMNAPOLB
SCHEMBL30843217 0.80 BCAT2 (0.67) KMT2ABCAT2GAALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744609-A REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-28 US claimed