Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.89 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | METAP2 | P50579 | 1/20 | 0.73 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.73 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.73 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.73 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | NSD2 | O96028 | 3/20 | 0.67 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680569 | 1.00 | KMT2A (0.89) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL1984940 | 0.94 | KMT2A (1.00) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL8635709 | 0.94 | KMT2A (1.00) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL9853965 | 0.91 | KMT2A (0.74) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL1979028 | 0.88 | KMT2A (0.71) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL7183285 | 0.88 | KMT2A (0.71) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL12181631 | 0.87 | ALDH1A1 (0.74) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL5312965 | 0.87 | KMT2A (0.69) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL6403159 | 0.87 | KMT2A (0.69) | KMT2AAPEX1HPGDGAALMNA | |
| SCHEMBL17686276 | 0.87 | HPGD (1.00) | KMT2AAPEX1HPGDGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372915-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-11-23 | — | — | US | disclosed |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-08-22 | — | — | US | disclosed |
| EP-3919466-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2021-12-08 | — | — | EP | disclosed |
| US-20150140588-A1 | Lipase Variants and Polynucleotides Encoding Same | NOVOZYMES A/S (DK) | 2015-05-21 | — | — | US | disclosed |
| US-8377530-B2 | Polyesters with low molecular weight additives for improved gas barrier properties | EASTMAN CHEMICAL COMPANY (US) | 2013-02-19 | — | — | US | disclosed |
| US-20120199515-A1 | POLYESTERS WITH LOW MOLECULAR WEIGHT ADDITIVES FOR IMPROVED GAS BARRIER PROPERTIES | EASTMAN CHEMICAL COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372915-A1 | MANGANESE BASED COMPLEXES AND USES THEREOF FOR HOMOGENEOUS CATALYSIS | ADH1C, OTC, MLEC | KMT2A 843/4885APEX1 1048/4885HPGD 2241/4885 |
| US-11731116-B2 | Manganese based complexes and uses thereof for homogeneous catalysis | ADH1C, OTC, ADH5 | KMT2A 990/4885APEX1 996/4885HPGD 2313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.