SCHEMBL8622236

SCHEMBL8622236

C[Si](C)(O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5712096 1.00
SCHEMBL9012662 0.98
SCHEMBL9546029 0.91
SCHEMBL18021010 0.85
SCHEMBL18021012 0.85
SCHEMBL5665490 0.84
SCHEMBL5050715 0.82 LMNA (0.31)
SCHEMBL7064601 0.82 THRB (0.31)
SCHEMBL7059728 0.82 THRB (0.31)
SCHEMBL5666450 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8143424-A None JP disclosed
JP-2042089-A None JP disclosed
JP-2042090-A None JP disclosed
US-9725619-B2 Composition including silicon-containing compounds ACULON, INC. (US) 2017-08-08 US disclosed
US-20160230045-A1 Composition Including Silicon-Containing Compounds ACULON, INC. 2016-08-11 US disclosed
EP-0635533-B1 Polyimide-based liquid crystal aligning agent SAGAMI CHEM RES (JP) 1998-06-10 EP disclosed
JP-H08143424-A COSMETIC AND SURFACE TREATING AGENT SHISEIDO CO LTD 1996-06-04 JP disclosed
EP-0452725-B1 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEM RES (JP) 1995-11-08 EP disclosed
EP-0635533-A1 Polyimide-based liquid crystal aligning agent SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP disclosed
US-5153304-A Polyimides; liquid crystal tilting agent; water-repelling SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-10-06 US disclosed
US-5047491-A Molding materials; waterproofing, oil repellents, antifouling agents CHISSO CORPORATION (JP) 1991-09-10 US disclosed
US-4996280-A Polyorganosiloxane compounds with amino group CHISSO CORPORATION (JP) 1991-02-26 US disclosed
US-4992521-A Oil and water repellency, stain and heat resistance, release properties CHISSO CORPORATION (JP) 1991-02-12 US disclosed
US-4987203-A Modifier of properties of epoxy resins, polyamides or polyurethanes CHISSO CORPORATION (JP) 1991-01-22 US disclosed
EP-0355497-A2 Polyorganosiloxane compounds Chisso Corporation (JP) 1990-02-28 EP disclosed
JP-H0242090-A ORGANOSILOXANE COMPOUND HAVING AMINO GROUP CHISSO CORP 1990-02-13 JP disclosed
JP-H0242089-A ORGANOSILOXANE COMPOUND CHISSO CORP 1990-02-13 JP disclosed
EP-0353709-A2 Polyorganosiloxane compounds with amino group Chisso Corporation (JP) 1990-02-07 EP disclosed
EP-0349920-A2 Polyorganosiloxane Chisso Corporation (JP) 1990-01-10 EP disclosed
EP-0338577-A2 Organosiloxane and process for preparing the same Chisso Corporation (JP) 1989-10-25 EP disclosed