Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL840882 | 0.76 | USP2 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13406732 | 0.68 | KDM4E (0.33) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL13406733 | 0.67 | KDM4E (0.32) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL783382 | 0.65 | USP2 (0.56) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL5873343 | 0.65 | — | — | |
| SCHEMBL5070659 | 0.64 | — | — | |
| SCHEMBL29840591 | 0.63 | USP2 (0.53) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| Benzene SCHEMBL28313098 | 0.58 | USP2 (0.42) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL25630388 | 0.58 | USP2 (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL5873341 | 0.58 | TSHR (0.52) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143406-B2 | Process for the manufacture of HI-6 dimethanesulfonate | PHOENIX CHEMICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| US-20100016604-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | PHOENIX CHEMICALS LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016604-A1 | PROCESS FOR THE MANUFACTURE OF HI-6 DIMETHANESULFONATE | DHX36, HAAO, INTS6 | KDM4E 808/4885USP2 1675/4885ALDH1A1 727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.