Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27571883 | 0.86 | TSHR (0.60) | TSHRCA2CA1CA9AR | |
| SCHEMBL249386 | 0.84 | CA2 (0.63) | TSHRCA2CA1CA9AR | |
| Benzene SCHEMBL27447210 | 0.84 | CA2 (0.63) | TSHRCA2CA1CA9AR | |
| SCHEMBL2076848 | 0.83 | TSHR (0.50) | TSHRCA2CA1CA9AR | |
| SCHEMBL30388469 | 0.81 | TSHR (0.48) | TSHRCA2CA1CA9AR | |
| SCHEMBL12013298 | 0.81 | TSHR (0.48) | TSHRCA2CA1CA9AR | |
| SCHEMBL6379981 | 0.81 | TSHR (0.48) | TSHRCA2CA1CA9AR | |
| SCHEMBL10316643 | 0.81 | TSHR (0.48) | TSHRCA2CA1CA9AR | |
| SCHEMBL25622617 | 0.81 | TSHR (0.48) | TSHRCA2CA1CA9AR | |
| SCHEMBL2078239 | 0.80 | ALDH1A1 (0.52) | TSHRCA2CA1CA9AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543243-B1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL DERIVATIVES | AQDOT LTD (GB) | 2022-02-02 | — | — | EP | claimed |
| US-10626119-B2 | Process for the preparation of cucurbituril and/or one or more derivatives thereof | AQDOT LIMITED (GB) | 2020-04-21 | — | — | US | claimed |
| EP-3543243-A1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL DERIVATIVES | Aqdot Limited (GB) | 2019-09-25 | — | — | EP | claimed |
| US-20190241579-A1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL AND/OR ONE OR MORE DERIVATIVES THEREOF | AQDOT LIMITED (GB) | 2019-08-08 | — | — | US | claimed |
| US-20180244681-A1 | PROCESS | AQDOT LIMITED (GB) | 2018-08-30 | — | — | US | claimed |
| WO-2018115822-A1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL DERIVATIVES | AQDOT LIMITED (GB) | 2018-06-28 | — | — | WO | claimed |
| US-RE38934-E1 | Method and reagents for N-alkylating ureides | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-01-10 | — | — | US | claimed |
| CN-1193019-C | Process and reagent for N-alkylation of ureides | TARO PHARMA IND (IL) | 2005-03-16 | — | — | CN | claimed |
| US-20040167358-A1 | Method and reagents for N-alkylating ureides | GUTMAN DANIELA (IL) | 2004-08-26 | — | — | US | claimed |
| EP-1027339-B1 | METHOD AND REAGENTS FOR N-ALKYLATING UREIDES | TARO PHARMA IND (IL) | 2004-01-02 | — | — | EP | claimed |
| US-20030018080-A1 | N-methoxymethyl-5,5-diphenylbarbituric acid | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2003-01-23 | — | — | US | claimed |
| CN-1273581-A | Process and reagent for N-alkylation of ureides | TARO PHARMA IND (IL) | 2000-11-15 | — | — | CN | claimed |
| US-6093820-A | REACTING AN IMIDE WITH A (SUBSTITUTED)ALKOXYALKYLSULFONIC ACID ESTER TO FORM A N-ALKOXYALKYL IMIDE SUCH AS METHOXYMETHYL ETHOSUXIMIDE; ADMINISTERING AS ANTICONVULSANT, ANTIANXIETY AGENT AND MUSCLE RELAXANT | TARO PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2000-07-25 | — | — | US | claimed |
| EP-3543243-B1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL DERIVATIVES | AQDOT LTD (GB) | 2022-02-02 | — | — | EP | disclosed |
| US-10626119-B2 | Process for the preparation of cucurbituril and/or one or more derivatives thereof | AQDOT LIMITED (GB) | 2020-04-21 | — | — | US | disclosed |
| EP-3543243-A1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL DERIVATIVES | Aqdot Limited (GB) | 2019-09-25 | — | — | EP | disclosed |
| EP-1027339-B1 | METHOD AND REAGENTS FOR N-ALKYLATING UREIDES | TARO PHARMA IND (IL) | 2004-01-02 | — | — | EP | disclosed |
| US-6664262-B2 | N-methoxymethyl-5,5-diphenylbarbituric acid | TARO PHARMACEUTICALS INDUSTRIES LTD. (IL) | 2003-12-16 | — | — | US | disclosed |
| EP-1342718-A1 | Method and reagents for n-alkylating ureides | TARO PHARMACEUTICAL INDUSTRIES LIMITED (IL) | 2003-09-10 | — | — | EP | disclosed |
| CN-1273581-A | Process and reagent for N-alkylation of ureides | TARO PHARMA IND (IL) | 2000-11-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180244681-A1 | PROCESS | UCHL3, UCHL5, CBR3 | TSHR 4166/4885CA2 4098/4885CA1 3884/4885 |
| US-20030018080-A1 | N-methoxymethyl-5,5-diphenylbarbituric acid | MGMT, ALKBH3, ALKBH5 | TSHR 3284/4885CA2 368/4885CA1 645/4885 |
| US-10626119-B2 | Process for the preparation of cucurbituril and/or one or more derivatives thereof | UCHL3, UCHL1, UCHL5 | TSHR 3492/4885CA2 4288/4885CA1 3958/4885 |
| US-20040167358-A1 | Method and reagents for N-alkylating ureides | MGMT, ETV6, ALKBH3 | TSHR 3045/4885CA2 257/4885CA1 358/4885 |
| US-20190241579-A1 | PROCESS FOR THE PREPARATION OF CUCURBITURIL AND/OR ONE OR MORE DERIVATIVES THEREOF | UCHL3, UCHL1, UCHL5 | TSHR 3492/4885CA2 4288/4885CA1 3958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.