SCHEMBL862260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29735438	1.00	CYP2A6 (0.38)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL825667	0.89	CYP2A6 (0.39)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL1609993	0.89	CYP2A6 (0.42)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL862523	0.87	BCL2L1 (0.43)	CYP2A6CYP1A2BCL2L1MCL1ALDH1A1
	SCHEMBL22738420	0.86	CYP2A6 (0.38)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL10068340	0.84	BCL2L1 (0.44)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL11976505	0.83	GAA (0.42)	ALDH1A1POLBHPGDMAPTGAA
	SCHEMBL22738447	0.83	BCL2L1 (0.43)	CYP2A6CYP1A2IDO1BCL2L1MCL1
	SCHEMBL10133869	0.80	MAPT (0.40)	CYP2A6CYP1A2IDO1ALDH1A1KDM4E
	SCHEMBL10133864	0.79	BCL2L1 (0.38)	CYP2A6IDO1BCL2L1MCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.