SCHEMBL10133864

SCHEMBL10133864

Cc1ccc2sc3cc(-c4ccc5c(c4)sc4ccc(C)cc45)ccc3c2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.38
MCL1 Q07820 1/20 0.38
MAPT P10636 5/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HPGD P15428 2/20 0.37
TP53 P04637 1/20 0.37
ESR1 P03372 1/20 0.36
IDO1 P14902 2/20 0.35
GPR3 P46089 1/20 0.34
CYP2A6 P11509 1/20 0.34
APP P05067 3/20 0.33
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 2/20 0.33
GAA P10253 2/20 0.33
POLB P06746 2/20 0.33
GLA P06280 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25811188 0.96 ESR1 (0.37) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL15315604 0.93 ALDH1A1 (0.37) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL10133866 0.92 BCL2L1 (0.41) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL19010386 0.91 LIMK1 (0.41) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL25517177 0.90 IDO1 (0.33) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL10133869 0.90 MAPT (0.40) MAPTALDH1A1RAB9ASMN1; SMN2HPGD
SCHEMBL10068340 0.90 BCL2L1 (0.44) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL10133862 0.90 BCL2L1 (0.44) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL22738447 0.88 BCL2L1 (0.43) BCL2L1MCL1MAPTALDH1A1RAB9A
SCHEMBL15599413 0.86 MCL1 (0.40) BCL2L1MCL1MAPTRAB9AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-8847141-B2 Photoelectric conversion element, production method thereof, photosensor, imaging device and their driving method FUJIFILM CORPORATION (JP) 2014-09-30 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed
US-8637860-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2014-01-28 US disclosed
US-20130122276-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2013-05-16 US disclosed
US-8378339-B2 Photoelectric conversion device, production method thereof, photosensor, imaging device and their drive methods FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS FUJIFILM CORPORATION (JP) 2011-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX BCL2L1 4273/4885MCL1 4751/4885MAPT 342/4885
US-20110063485-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVE METHODS PPOX, CRY1, FTO BCL2L1 3704/4885MCL1 4269/4885MAPT 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.