Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620555 | 0.92 | TDP1 (0.55) | TDP1RORCPLCG2RXFP1PCTP | |
| SCHEMBL8624438 | 0.89 | TDP1 (0.62) | TDP1RORCPLCG2RXFP1PCTP | |
| SCHEMBL8662539 | 0.88 | GCGR (0.65) | TDP1PLCG2LMNAMAPTHTT | |
| SCHEMBL8662540 | 0.87 | TDP1 (0.59) | TDP1RORCPLCG2RXFP1LMNA | |
| SCHEMBL8620837 | 0.86 | PYGL (0.46) | TDP1RORCPLCG2RXFP1SMN1; SMN2 | |
| SCHEMBL8621586 | 0.84 | IL2 (0.54) | MAPTALDH1A1MEN1KMT2AGAA | |
| Chlotrifmeuron SCHEMBL10868747 | 0.84 | TDP1 (0.70) | TDP1RORCPLCG2RXFP1PCTP | |
| SCHEMBL11138807 | 0.84 | GCGR (0.62) | TDP1PLCG2PCTPLMNAMAPT | |
| SCHEMBL9743052 | 0.82 | TRPV1 (0.47) | TDP1RORCPLCG2RXFP1SMN1; SMN2 | |
| SCHEMBL11766283 | 0.81 | MAPT (0.49) | MAPTALDH1A1KMT2AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854288-A | Use of benzoylureas for controlling house dust mites | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-29 | — | — | US | disclosed |
| EP-0729301-A1 | USE OF BENZOYLUREAS FOR CONTROLLING HOUSE DUST MITES | Hoechst Schering AgrEvo GmbH (DE) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995013703-A1 | USE OF BENZOYLUREAS FOR CONTROLLING HOUSE DUST MITES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-05-26 | — | — | WO | disclosed |