Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | GCGR | P47871 | 1/20 | 0.52 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.43 |
| ▸ | BRAF | P15056 | 3/20 | 0.43 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | TNNI3K | Q59H18 | 3/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | LYN | P07948 | 2/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620555 | 0.89 | TDP1 (0.55) | TDP1GCGRRORCKDRPLCG2 | |
| SCHEMBL8622701 | 0.87 | TDP1 (0.55) | TDP1GCGRRORCKDRPLCG2 | |
| SCHEMBL8657705 | 0.86 | TLR8 (0.60) | TLR8TLR7RAF1KDRBRAF | |
| SCHEMBL8661111 | 0.86 | TDP1 (0.58) | TDP1GCGRTLR8TLR7RORC | |
| SCHEMBL8662539 | 0.86 | GCGR (0.65) | TDP1GCGRPLCG2HTTPOLB | |
| SCHEMBL8659897 | 0.85 | GCGR (0.72) | TDP1GCGRTLR8TLR7RORC | |
| SCHEMBL8656261 | 0.85 | TLR8 (0.49) | TLR8TLR7RAF1KDRBRAF | |
| SCHEMBL9325879 | 0.83 | GCGR (0.69) | TDP1GCGRTLR8TLR7RORC | |
| Chlotrifmeuron SCHEMBL10868747 | 0.80 | TDP1 (0.70) | TDP1GCGRRORCPLCG2ALDH1A1 | |
| SCHEMBL9743052 | 0.80 | TRPV1 (0.47) | TDP1RORCKDRPLCG2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |