Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.78 |
| ▸ | CETP | P11597 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 3/20 | 0.74 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.73 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.52 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetyl Ceramide SCHEMBL12648655 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL12330743 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL29144648 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL1191825 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL58536 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL31683764 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL29756043 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL16892474 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL21067736 | 0.88 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL14175577 | 0.87 | CETP (0.82) | MAPTCYP2D6MAPK1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792858-A | ACYLATING LYSOSPHINGOLIPIDS AND THEIR DERIVATIVES WITH AN ALIPHATIC ACID HAVING 2 TO 24 CARBON ATOMS, SUBSTITUTED BY ONE OR MORE POLAR GROUPS; PROTEIN-KINASE INHIBITOR, USEFUL FOR NERVOUS SYSTEM DISORDER TREATMENT | FIDIA S.P.A. (IT) | 1998-08-11 | — | — | US | disclosed |