Acetyl Ceramide

Acetyl Ceramide

SCHEMBL58536

CCCCCCCCCCCCCC=CC(O)C(CO)NC(C)=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
CYP2D6 P10635 3/20 1.00
MAPK1 P28482 3/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2C9 P11712 2/20 1.00
CYP2C19 P33261 2/20 1.00
CETP P11597 7/20 0.75
MEN1 O00255 4/20 0.75
KMT2A Q03164 4/20 0.75
THRB P10828 3/20 0.75
ASAH1 Q13510 2/20 0.73
ASAH2 Q9NR71 2/20 0.71
ALDH1A1 P00352 2/20 0.65
KDM4E B2RXH2 1/20 0.65
SPHK2 Q9NRA0 4/20 0.55
SPHK1 Q9NYA1 4/20 0.55
GMNN O75496 2/20 0.55
LMNA P02545 2/20 0.55
GLA P06280 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetyl Ceramide SCHEMBL21067736 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL31683764 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL12648655 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL12330743 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL16892474 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL1191825 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL29144648 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
Acetyl Ceramide SCHEMBL29756043 1.00 MAPT (1.00) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL12764186 0.90 MAPT (0.81) MAPTCYP2D6MAPK1TP53CYP1A2
SCHEMBL8622716 0.88 MAPT (0.78) MAPTCYP2D6MAPK1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223352-B1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC INC (US) 2026-05-27 EP claimed
US-12605342-B2 Polymer-encapsulated drug particles TONIC MEDICAL, INC. (US) 2026-04-21 US claimed
CN-116508751-B Method for preventing and controlling harmful algae in water body by using sphingosine substances 浙江大学 2025-05-13 CN claimed
US-12280226-B2 Drug-coated balloon catheters for body lumens UROTRONIC, INC. (US) 2025-04-22 US claimed
CN-119733157-A Drug coated balloon catheter for non-vascular stenosis 江苏长寿棒科技有限公司 2025-04-01 CN claimed
US-20250082582-A1 POLYMER-ENCAPSULATED DRUG PARTICLES TONIC MEDICAL, INC. 2025-03-13 US claimed
US-20250025673-A1 METHOD FOR TREATMENT OF AIRWAY STRICTURE OR STENOSIS AIRIVER MEDICAL, INC. 2025-01-23 US claimed
CN-119303213-A Drug-coated balloon catheter for body cavities 优敦力公司 2025-01-14 CN claimed
US-20240416013-A1 DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS UROTRONIC, INC. 2024-12-19 US claimed
US-12168108-B2 Balloon catheters for body lumens UROTRONIC, INC. (US) 2024-12-17 US claimed
US-20100056482-A1 Calixarene Derivatives as Anticancer Agent CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS (FR) 2010-03-04 US claimed
US-20090196859-A1 Oligodendrocyte Precursor Cell Composition and Methods of Use MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) 2009-08-06 US claimed
US-7445931-B2 Culturing differentiating pluripotent human cell with N-palmitoyl serinol or N-oleoyl serinol in serum-free medium; modulating apoptosis BRESAGEN, INC. (US) 2008-11-04 US claimed
EP-1250119-B1 REDUCTION OF HAIR GROWTH GILLETTE CO (US) 2007-10-03 EP claimed
WO-2004080478-A1 THERAPEUTIC AND PROPHYLACTIC COMPOSITIONS AND USES THEREFOR THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2004-09-23 WO claimed
US-6204006-B1 TREATING PARENT STRAIN OF YEAST WHICH NATURALLY PRODUCES TETRAACETYLPHYTOSPHINGOSINE WITH A MUTAGEN AND SELECTING HIGH YIELD MUTANT STRAIN; FOR PRODUCTION OF AT LEAST 0.030 GRAMS PER YEAST DRY WEIGHT FROM SHAKING, LIQUID CULTURE DSM, N.V. (NL) 2001-03-20 US claimed
EP-0850056-A1 TOPICAL ANTI-SKIN-CANCER PREPARATIONS Beiersdorf Aktiengesellschaft (DE) 1998-07-01 EP claimed
WO-1997009975-A1 TOPICAL ANTI-SKIN-CANCER PREPARATIONS BEIERSDORF AG (DE) 1997-03-20 WO claimed
EP-0736770-A2 An immunoreactive conjugate, method for its preparation, antibodies to said conjugate and a pharmaceutical composition and diagnostic device containing them ANDA BIOLOGICALS S.A. (FR) 1996-10-09 EP claimed
US-5260288-A Administering an inflammation inhibitory amount THE BIOMEMBRANE INSTITUTE (US) 1993-11-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605342-B2 Polymer-encapsulated drug particles MUC1, SLC10A2, EGFR MAPT 940/4885CYP2D6 1296/4885MAPK1 3225/4885
US-20100056482-A1 Calixarene Derivatives as Anticancer Agent CALU, CALR, CALD1 MAPT 3476/4885CYP2D6 2092/4885MAPK1 1626/4885
US-20250082582-A1 POLYMER-ENCAPSULATED DRUG PARTICLES CD47, GRPR, HSPA5 MAPT 1693/4885CYP2D6 2886/4885MAPK1 3616/4885
US-20090196859-A1 Oligodendrocyte Precursor Cell Composition and Methods of Use SGMS1, S1PR1, S1PR3 MAPT 4359/4885CYP2D6 4804/4885MAPK1 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.