Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 2/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | CETP | P11597 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.75 |
| ▸ | THRB | P10828 | 3/20 | 0.75 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.73 |
| ▸ | ASAH2 | Q9NR71 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.55 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.55 |
| ▸ | GMNN | O75496 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetyl Ceramide SCHEMBL21067736 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL16892474 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL29756043 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL58536 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL1191825 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL31683764 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| Acetyl Ceramide SCHEMBL29144648 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL12330743 | 1.00 | MAPT (1.00) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL12764186 | 0.90 | MAPT (0.81) | MAPTCYP2D6MAPK1TP53CYP1A2 | |
| SCHEMBL8622716 | 0.88 | MAPT (0.78) | MAPTCYP2D6MAPK1TP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20100248264-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | HK PHARMACEUTICALS, INC. | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | MAPT 3419/4885CYP2D6 4323/4885MAPK1 4167/4885 |
| US-20100298168-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CHLSN, PTMS, SRMS | MAPT 2601/4885CYP2D6 4202/4885MAPK1 3918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.