Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622743 | 1.00 | SLC29A1 (0.49) | SLC29A1ADORA1ADORA3TSHRPMP22 | |
| SCHEMBL8622665 | 0.89 | SLC29A1 (0.50) | SLC29A1ADORA1ADORA3TSHRPMP22 | |
| SCHEMBL8622677 | 0.89 | SLC29A1 (0.50) | SLC29A1ADORA1ADORA3TSHRPMP22 | |
| SCHEMBL8617434 | 0.88 | ADORA3 (0.56) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8617438 | 0.88 | ADORA3 (0.56) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8619559 | 0.84 | EGFR (0.43) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8619557 | 0.84 | EGFR (0.43) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8618438 | 0.84 | SLC29A1 (0.51) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8618443 | 0.84 | SLC29A1 (0.51) | SLC29A1ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8616452 | 0.83 | EGFR (0.46) | SLC29A1ADORA1ADORA3ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5336764-A | 2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-08-09 | — | — | US | disclosed |