Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618438 | 1.00 | SLC29A1 (0.51) | SLC29A1ADORA3ADORA2AADORA2BPRMT5 | |
| SCHEMBL8617438 | 0.87 | ADORA3 (0.56) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8617434 | 0.87 | ADORA3 (0.56) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8622677 | 0.86 | SLC29A1 (0.50) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8622665 | 0.86 | SLC29A1 (0.50) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8619444 | 0.85 | SLC29A1 (0.47) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8619439 | 0.85 | SLC29A1 (0.47) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8622743 | 0.84 | SLC29A1 (0.49) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8622749 | 0.84 | SLC29A1 (0.49) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8622528 | 0.82 | BCHE (0.42) | SLC29A1ADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817799-A | 2'-Fluorofuranosyl derivatives and methods for preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0540686-B1 | 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES | US COMMERCE (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5336764-A | 2'-fluorofuranosyl derivatives and novel method of preparing 2'-fluoropyrimidine and 2'-fluoropurine nucleosides | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-08-09 | — | — | US | disclosed |