SCHEMBL8622754

SCHEMBL8622754

C=Cc1ccccc1COc1ccccc1-c1ccccc1C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
HPGD P15428 4/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CDK4 P11802 2/20 0.43
CCND1 P24385 2/20 0.43
KMT2A Q03164 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PTGDR2 Q9Y5Y4 1/20 0.39
ERN1 O75460 1/20 0.38
KDM4E B2RXH2 3/20 0.37
POLB P06746 1/20 0.37
RECQL P46063 1/20 0.37
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
LMNA P02545 4/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11055202 0.88 ALDH1A1 (0.59) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL23680080 0.79 ALDH1A1 (0.45) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL23679966 0.79 ALDH1A1 (0.45) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL8621031 0.78 ALDH1A1 (0.40) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL11229642 0.76 CD274 (0.37) ALDH1A1HPGDHTTSMN1; SMN2KMT2A
SCHEMBL23680011 0.76 CDK4 (0.46) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL23679909 0.76 CDK4 (0.43) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL23679918 0.76 MAPT (0.42) ALDH1A1HPGDHTTSMN1; SMN2CDK4
SCHEMBL11213550 0.75 HPGD (0.54) ALDH1A1HPGDHTTCDK4CCND1
SCHEMBL16368767 0.75 HPGD (0.40) ALDH1A1HPGDHTTSMN1; SMN2CDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0597510-B1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1998-06-10 EP claimed
US-5401633-A Immunology, label detection EASTMAN KODAK COMPANY (US) 1995-03-28 US claimed
EP-0597510-A1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-05-18 EP claimed
EP-0597510-B1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1998-06-10 EP disclosed
US-5401633-A Immunology, label detection EASTMAN KODAK COMPANY (US) 1995-03-28 US disclosed
EP-0597510-A1 Biologically active reagent prepared from aldehyde-containing polymer, test kit, analytical element and methods of use Johnson & Johnson Clinical Diagnostics, Inc. (US) 1994-05-18 EP disclosed
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed
US-4281207-A CROSSLINKING POLYMERS USEFUL IN RELIEF IMAGES, PHOTORESISTS, AND LITHOGRAPHIC PLATES EASTMAN KODAK COMPANY (US) 1981-07-28 US disclosed
US-4259469-A DESIRABLE SOLUBILITY CHARACTERISTICS FOR USE IN PHOTOLITHOGRAPHY EASTMAN KODAK COMPANY (US) 1981-03-31 US disclosed
US-4225689-A PHOTORESISTS, LITHOGRAPHIC PLATES, RELIF IMAGES EASTMAN KODAK COMPANY (US) 1980-09-30 US disclosed