Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622760 | 1.00 | TP53 (0.46) | TP53HTTPTGDR2RXRARXRB | |
| SCHEMBL674085 | 0.89 | HTT (0.47) | TP53HTTPTGDR2RXRARXRB | |
| SCHEMBL26650771 | 0.89 | HTT (0.47) | TP53HTTPTGDR2RXRARXRB | |
| SCHEMBL349565 | 0.89 | HTT (0.47) | TP53HTTPTGDR2RXRARXRB | |
| SCHEMBL8622780 | 0.89 | MRGPRX4 (0.50) | PTGDR2MRGPRX4HIF1AFFAR1FFAR4 | |
| SCHEMBL8622364 | 0.89 | PTGDR2 (0.44) | TP53HTTPTGDR2MRGPRX4HIF1A | |
| SCHEMBL8622779 | 0.89 | MRGPRX4 (0.50) | PTGDR2MRGPRX4HIF1AFFAR1FFAR4 | |
| SCHEMBL8622366 | 0.89 | PTGDR2 (0.44) | TP53HTTPTGDR2MRGPRX4HIF1A | |
| SCHEMBL8399010 | 0.88 | ALDH1A1 (0.42) | TP53HTTPTGDR2RXRARXRB | |
| SCHEMBL8399016 | 0.88 | ALDH1A1 (0.42) | TP53HTTPTGDR2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |