Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | POLG | P54098 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531609 | 1.00 | LMNA (0.40) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL13376173 | 0.83 | DNMT1 (0.45) | LMNAMTOR | |
| SCHEMBL17832132 | 0.82 | POLB (0.37) | MAPTPOLBNT5EP2RY6 | |
| SCHEMBL14946322 | 0.82 | LMNA (0.38) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL14946323 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL27056652 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL27065056 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL15765583 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL9964282 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT | |
| SCHEMBL12404744 | 0.81 | LMNA (0.47) | LMNAPDE3ACACNA1FALBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023215516-A2 | ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF | HELIX NANOTECHNOLOGIES, INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| US-5756704-A | Nucleosides and nucleoside derivatives containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5677441-A | Nucleosides, nucleotides and oligonucleotides containing enzymatically cleavable protecting groups | BOEHRINGER MANNHEIM GMBH (DE) | 1997-10-14 | — | — | US | disclosed |
| EP-0649855-A1 | Use of nucleosides and nucleoside derivatives with enzymatically cleavable protecting groupes in the synthesis of oligonucleotiden | Roche Diagnostics GmbH (DE) | 1995-04-26 | — | — | EP | disclosed |