Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.38 |
| ▸ | CA1 | P00915 | 17/20 | 0.38 |
| ▸ | CA9 | Q16790 | 17/20 | 0.38 |
| ▸ | CA12 | O43570 | 16/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037282 | 0.93 | CA2 (0.34) | CA2CA1CA9CA12CDK2 | |
| SCHEMBL8623643 | 0.86 | CA12 (0.47) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8619753 | 0.85 | CA12 (0.50) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL8622828 | 0.82 | CDK2 (0.38) | CA2CA1CA9CDK2KDM4E | |
| SCHEMBL8620831 | 0.81 | CA12 (0.46) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8617656 | 0.81 | CDK2 (0.38) | CA2CA1CA9CA12CDK2 | |
| SCHEMBL9037445 | 0.80 | CA12 (0.42) | CA2CA1CA9CA12CA4 | |
| SCHEMBL8623604 | 0.79 | CDK2 (0.37) | CA2CA1CA9CA12CDK2 | |
| SCHEMBL9037996 | 0.78 | CA12 (0.44) | CA2CA1CA9CA12KDM4E | |
| SCHEMBL8619762 | 0.77 | CA12 (0.46) | CA2CA1CA9CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |