Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 15/20 | 0.47 |
| ▸ | CA1 | P00915 | 15/20 | 0.47 |
| ▸ | CA2 | P00918 | 15/20 | 0.47 |
| ▸ | CA9 | Q16790 | 15/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037445 | 0.93 | CA12 (0.42) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8619762 | 0.87 | CA12 (0.46) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8623623 | 0.87 | CA12 (0.51) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8622818 | 0.86 | CA2 (0.38) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8620831 | 0.84 | CA12 (0.46) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8623647 | 0.84 | CDK2 (0.34) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8619763 | 0.82 | CA2 (0.40) | CA12CA1CA2CA9MAPT | |
| SCHEMBL8617972 | 0.81 | CA2 (0.39) | CA12CA1CA2CA9MAPT | |
| SCHEMBL9037282 | 0.80 | CA2 (0.34) | CA12CA1CA2CA9 | |
| SCHEMBL9036361 | 0.80 | CA12 (0.45) | CA12CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |