Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622652 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL8617969 | 0.77 | EPHX1 (0.46) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL30413006 | 0.77 | EPHX1 (0.46) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL8617873 | 0.77 | EPHX1 (0.46) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL8618966 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL293955 | 0.74 | EPHX1 (0.56) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL23256074 | 0.74 | EPHX1 (0.58) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL21610579 | 0.74 | EPHX1 (0.58) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL30078348 | 0.74 | EPHX1 (0.58) | ALDH1A1HPGDCYP19A1EPHX1LMNA | |
| SCHEMBL16194851 | 0.73 | EPHX1 (0.61) | ALDH1A1HPGDCYP19A1EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763451-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-09 | — | — | US | disclosed |