Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642559 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL8622835 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL18585621 | 0.74 | ALDH1A1 (0.53) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL13560800 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL1862739 | 0.73 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL28473708 | 0.72 | ALDH1A1 (0.83) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL4732797 | 0.72 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL29906119 | 0.71 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL21547326 | 0.71 | ALDH1A1 (0.72) | ALDH1A1HPGDCYP19A1EPHX1MAPT | |
| SCHEMBL9493633 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HPGDCYP19A1EPHX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763451-A | Dynemicin analogs | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-09 | — | — | US | disclosed |