Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621438 | 0.93 | MAPT (0.41) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8618782 | 0.93 | HPGD (0.35) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8622978 | 0.90 | MAPT (0.43) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8618866 | 0.86 | MAPT (0.45) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8622167 | 0.86 | MAPT (0.35) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8624121 | 0.82 | MAPT (0.37) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8621400 | 0.82 | MAPT (0.43) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8622844 | 0.81 | LMNA (0.41) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8616781 | 0.78 | MAPT (0.38) | LMNAHPGDATMMAPTALDH1A1 | |
| SCHEMBL8621708 | 0.78 | MAPT (0.50) | LMNAHPGDATMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |