SCHEMBL8622933

SCHEMBL8622933

CCCCCCCC=C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 14/20 0.64
ESR2 Q92731 14/20 0.64
HSD17B3 P37058 6/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3844004 0.92 ESR1 (0.62) ESR1ESR2HSD17B3
SCHEMBL16685069 0.84 ESR1 (0.50) ESR1ESR2HSD17B3
SCHEMBL11506636 0.84 HSD17B3 (0.50) ESR1ESR2HSD17B3
SCHEMBL11506634 0.84 HSD17B3 (0.50) ESR1ESR2HSD17B3
SCHEMBL11792681 0.83 TBXAS1 (0.54) ESR1ESR2
SCHEMBL7861116 0.83 TBXAS1 (0.54) ESR1ESR2
SCHEMBL28251847 0.83 TBXAS1 (0.54) ESR1ESR2
SCHEMBL11229130 0.83 TBXAS1 (0.54) ESR1ESR2
SCHEMBL9169660 0.83 TBXAS1 (0.54) ESR1ESR2
SCHEMBL8418666 0.83 TBXAS1 (0.54) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659582-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 1998-05-13 EP disclosed
US-5558700-A QUINAZOLENE OR PYRIDINE ELECTRON DONOR, ELECTRON ACCEPTOR THE PILOT INK CO., LTD. (JP) 1996-09-24 US disclosed
EP-0659582-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1995-06-28 EP disclosed