Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17121964 | 1.00 | LMNA (0.68) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL8850325 | 0.82 | LMNA (1.00) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL29522421 | 0.82 | LMNA (1.00) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL8621721 | 0.81 | LMNA (0.67) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL9073907 | 0.80 | LMNA (0.57) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL27284117 | 0.80 | LMNA (0.68) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL9147388 | 0.73 | LMNA (0.79) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL13925444 | 0.72 | NPSR1 (1.00) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL28985711 | 0.72 | ALDH1A1 (0.76) | LMNANPSR1TSHRMAPK1USP2 | |
| SCHEMBL6649203 | 0.72 | LMNA (0.65) | LMNANPSR1TSHRMAPK1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728869-A | Processes for the preparation of pesticides and intermediates | AMERICAN CYANAMID COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5521317-A | Processes for the preparation of pesticides and intermediates | AMERICAN CYANAMID CO. (US) | 1996-05-28 | — | — | US | disclosed |
| EP-0654464-A1 | Processes for the preparation of pesticides and intermediates | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-05-24 | — | — | EP | disclosed |