Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554226 | 0.83 | SMN1; SMN2 (0.47) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8621609 | 0.76 | SMN1; SMN2 (0.51) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8549475 | 0.71 | SMN1; SMN2 (0.65) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8626988 | 0.70 | GRIN2B (0.52) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8552717 | 0.69 | LMNA (0.47) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8552715 | 0.69 | LMNA (0.47) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8549063 | 0.69 | TSHR (0.53) | GRIN2BSMN1; SMN2CYP2C19NPC1RAB9A | |
| SCHEMBL9377530 | 0.69 | BCHE (0.47) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL8549687 | 0.69 | HTT (0.47) | FAAHGRIN2BSMN1; SMN2CYP2C19NPC1 | |
| SCHEMBL17485189 | 0.65 | MAPT (0.58) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817677-A | ANTITHROMBOSIS AGENTS | DR. KARL THOMAE GMBH (DE) | 1998-10-06 | — | — | US | disclosed |