Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624261 | 0.84 | — | — | |
| SCHEMBL8621297 | 0.83 | IDO1 (0.36) | ALDH1A1IDO1TACR1 | |
| SCHEMBL252296 | 0.80 | ALDH1A1 (0.43) | ALDH1A1IDO1TACR1 | |
| SCHEMBL9193381 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9193908 | 0.80 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL4906826 | 0.78 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL6095648 | 0.76 | IDO1 (0.50) | ALDH1A1IDO1TACR1 | |
| SCHEMBL9544583 | 0.75 | L3MBTL1 (0.35) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL759640 | 0.75 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL4908049 | 0.75 | CA1 (0.39) | ALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786434-A | A CURABLE COPOLYMER COMPRISING A DIALKYLACRYLAMIDE OR METHACRYLAMIDE, A VINYLLACTAM, A BIS(SILICON-CONTAINING ALKYL)FUMARATE MONOMERS; RADIATION TRANSPARENT, HIGH OXYGEN PERMEABILITY | MENICON CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |