Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 6/20 | 0.47 |
| ▸ | CNR1 | P21554 | 9/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623017 | 0.93 | FDFT1 (0.41) | FDFT1CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL8624863 | 0.87 | FDFT1 (0.51) | FDFT1CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL8623156 | 0.86 | SIGMAR1 (0.44) | FDFT1CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL8619446 | 0.84 | FDFT1 (0.47) | FDFT1CNR1CNR2CYP1A2CYP2D6 | |
| SCHEMBL8191921 | 0.80 | CNR1 (0.48) | CNR1CNR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8623571 | 0.80 | FDFT1 (0.40) | FDFT1CNR1CNR2CYP1A2CYP2C19 | |
| SCHEMBL8200283 | 0.79 | CNR1 (0.42) | CNR1CNR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8200289 | 0.79 | CNR1 (0.42) | CNR1CNR2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8621728 | 0.79 | FDFT1 (0.47) | FDFT1CNR1CNR2CYP1A2CYP2C19 | |
| SCHEMBL8621712 | 0.78 | SIGMAR1 (0.47) | CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |