Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 12/20 | 0.45 |
| ▸ | CNR2 | P34972 | 9/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619446 | 0.98 | FDFT1 (0.47) | FDFT1CYP1A2CYP2D6CYP2C19CNR1 | |
| SCHEMBL8623156 | 0.92 | SIGMAR1 (0.44) | FDFT1CYP1A2CYP2D6CYP2C19CNR1 | |
| SCHEMBL8621712 | 0.91 | SIGMAR1 (0.47) | CYP1A2CYP2D6SIGMAR1ALDH1A1LMNA | |
| SCHEMBL8625050 | 0.89 | FDFT1 (0.47) | FDFT1CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL8191921 | 0.88 | CNR1 (0.48) | CYP1A2CYP2D6CYP2C19CNR1CNR2 | |
| SCHEMBL8623017 | 0.87 | FDFT1 (0.41) | FDFT1CYP1A2CYP2D6CYP2C19CNR1 | |
| SCHEMBL8623569 | 0.87 | FDFT1 (0.47) | FDFT1CYP1A2CYP2D6CYP2C19CNR1 | |
| SCHEMBL8200289 | 0.83 | CNR1 (0.42) | CYP1A2CYP2D6CYP2C19CNR1CNR2 | |
| SCHEMBL8200283 | 0.83 | CNR1 (0.42) | CYP1A2CYP2D6CYP2C19CNR1CNR2 | |
| SCHEMBL8128392 | 0.82 | CYP1A2 (0.45) | CYP1A2CYP2D6CYP2C19CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5777150-A | Substituted amic acid derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1998-07-07 | — | — | US | disclosed |