SCHEMBL8623574

SCHEMBL8623574

Cc1cc2c(cc1C)C(=N)NC2=N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
HSD17B10 Q99714 1/20 0.37
HTT P42858 1/20 0.33
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
POLB P06746 1/20 0.31
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31
BCHE P06276 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29970054 1.00 ALDH1A1 (0.37) ALDH1A1KDM4EHPGDLMNAMAPT
SCHEMBL21573605 0.83 HTT (0.40) ALDH1A1KDM4EHPGDLMNAMAPT
SCHEMBL18663486 0.71
SCHEMBL18663475 0.71 AHR (0.30)
SCHEMBL1134711 0.69 CYP3A4 (0.41) ALDH1A1KDM4EHPGDLMNAMAPT
SCHEMBL11622426 0.67 TDP2 (0.46) POLB
SCHEMBL4957649 0.65
SCHEMBL7278521 0.65 GSK3B (0.47) ALDH1A1KDM4EHPGDLMNAMAPT
SCHEMBL27832465 0.65 TSHR (0.53) ALDH1A1KDM4EHPGDLMNAMAPT
SCHEMBL4263339 0.64 ALDH1A1 (0.40) ALDH1A1KDM4EHPGDLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US disclosed
CN-117529520-A Fluoroelastomer compositions containing curative 杜邦特种产品美国有限公司 2024-02-06 CN disclosed
EP-4305096-A1 FLUOROELASTOMERS COMPOSITION COMPRISING CURING AGENTS Dupont Specialty Products USA, LLC (US) 2024-01-17 EP disclosed
EP-3521378-B1 PYRIMIDOQUINAZOLINE PIGMENT, METHOD FOR MANUFACTURING PYRIMIDOQUINAZOLINE PIGMENT, AND PIGMENT COLORANT DAINICHISEIKA COLOR CHEM (JP) 2022-07-06 EP disclosed
US-10655017-B2 Pyrimidoquinazoline pigment, method for manufacturing pyrimidoquinazoline pigment, and pigment colorant DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2020-05-19 US disclosed
EP-3521378-A1 PYRIMIDOQUINAZOLINE PIGMENT, METHOD FOR MANUFACTURING PYRIMIDOQUINAZOLINE PIGMENT, AND PIGMENT COLORANT Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2019-08-07 EP disclosed
US-20190233649-A1 PYRIMIDOQUINAZOLINE PIGMENT, METHOD FOR MANUFACTURING PYRIMIDOQUINAZOLINE PIGMENT, AND PIGMENT COLORANT DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2019-08-01 US disclosed
US-7737270-B2 Method for producing a pigment CANON KABUSHIKI KAISHA (JP) 2010-06-15 US disclosed
US-7737270-B2 Method for producing a pigment CANON KABUSHIKI KAISHA (JP) 2010-06-15 US disclosed
US-20080182984-A1 METHOD FOR PRODUCING A PIGMENT CANON KABUSHIKI KAISHA (JP) 2008-07-31 US disclosed
US-20080182984-A1 METHOD FOR PRODUCING A PIGMENT CANON KABUSHIKI KAISHA (JP) 2008-07-31 US disclosed
US-5756247-A PHOTOCONDUCTOR OBTAINED BY HYDROXYLATION WITH ACID PASTING GALLIUM PHTHALOCYANINE; CHARGEABILITY, IMAGE; SEMICONDUCTOR LASER PRINTER FUJI XEROX CO., LTD. (JP) 1998-05-26 US disclosed
US-5663327-A Hydroxygallium phthalocyanine crystal, process for producing the same, and electrophotographic photoreceptor containing the same FUJI XEROX CO., LTD. (JP) 1997-09-02 US disclosed