SCHEMBL8623618

SCHEMBL8623618

CC(C)CC(C)CC(N)=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.42
CACNA2D1 P54289 2/20 0.41
CACNB3 P54284 1/20 0.41
CACNA1C Q13936 1/20 0.41
PGR P06401 1/20 0.41
ADRA1A P35348 1/20 0.41
HTR2B P41595 1/20 0.41
CACNA2D2 Q9NY47 1/20 0.41
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
RNPEP Q9H4A4 1/20 0.37
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37
ANPEP P15144 4/20 0.36
LAP3 P28838 2/20 0.36
ERAP1 Q9NZ08 1/20 0.36
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
CA2 P00918 1/20 0.35
ECE1 P42892 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11413659 0.89 ECE1 (0.35) SLC7A5CACNA2D1CACNB3CACNA1CPGR
Tricarballylic Acid SCHEMBL9979059 0.84 CACNA2D1 (0.44) SLC7A5CACNA2D1CACNB3CACNA1CPGR
SCHEMBL9979307 0.84 TDP1 (0.52) SLC7A5CACNA2D1CACNB3CACNA1CPGR
SCHEMBL3392036 0.83 ALDH1A1 (0.38) CACNA2D1CACNB3CACNA1CPGRADRA1A
SCHEMBL28225423 0.83 SLC1A3 (0.57) SLC7A5CACNA2D1CACNB3CACNA1CPGR
SCHEMBL27368082 0.82 ECE1 (0.32) SLC7A5CACNA2D1CACNB3CACNA1CPGR
SCHEMBL9105209 0.79 CACNA2D1 (0.52) SLC7A5CACNA2D1CACNB3CACNA1CPGR
SCHEMBL4659755 0.79 CACNA2D1 (0.52) SLC7A5CACNA2D1CACNB3CACNA1CPGR
Acetamide SCHEMBL4103797 0.78 LMNA (0.47) CACNA2D1CACNB3CACNA1CALDH1A1TDP1
SCHEMBL28032352 0.78 ALDH1A1 (0.41) SLC7A5CACNA2D1CACNB3CACNA1CPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821675-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1998-02-04 EP claimed
WO-1996033176-A1 NOVEL HYDROXAMIC ACID AND AMINO-CARBOXYLATE COMPOUNDS AS METALLOPROTEASE AND TNF INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-10-24 WO claimed