Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 12/20 | 0.51 |
| ▸ | CA2 | P00918 | 12/20 | 0.51 |
| ▸ | CA9 | Q16790 | 12/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036361 | 0.93 | CA12 (0.45) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8616761 | 0.88 | CA12 (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8619753 | 0.88 | CA12 (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8623643 | 0.87 | CA12 (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8620056 | 0.85 | CA12 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8623629 | 0.83 | CA12 (0.36) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8621394 | 0.81 | KDM4E (0.50) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL9037445 | 0.80 | CA12 (0.42) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL9037996 | 0.80 | CA12 (0.44) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL8616856 | 0.79 | KDM4E (0.48) | CA12CA1CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710138-A | Benzo f!quinoxalinedione derivatives, their production and use in pharmaceutical agents | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| EP-0696289-B1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 1997-03-12 | — | — | EP | disclosed |
| WO-1994025470-A1 | BENZO[F]QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |