Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 7/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830018 | 0.88 | MEN1 (0.39) | ALDH1A1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8625156 | 0.86 | KDM4E (0.50) | ALDH1A1KDM4EHPGDTDP1MTNR1A | |
| SCHEMBL8830016 | 0.83 | KMT2A (0.40) | ALDH1A1KDM4EMEN1KMT2AMTNR1A | |
| SCHEMBL8623913 | 0.82 | KDM4E (0.46) | ALDH1A1KDM4EHPGDTDP1PTGDR2 | |
| SCHEMBL8627326 | 0.79 | MTNR1A (0.48) | ALDH1A1KDM4EHPGDTDP1MTNR1A | |
| SCHEMBL8625004 | 0.76 | KDM4E (0.50) | ALDH1A1KDM4EHPGDTDP1MTNR1A | |
| SCHEMBL8602034 | 0.75 | KMT2A (0.41) | ALDH1A1MEN1KMT2AADAMTS4ADAMTS5 | |
| SCHEMBL8625506 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL8624608 | 0.73 | KDM4E (0.46) | ALDH1A1KDM4EHPGDTDP1CASP1 | |
| SCHEMBL7958710 | 0.72 | PTGIR (0.64) | ALDH1A1KDM4EHPGDTDP1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| CN-1111612-A | Naphthyloxyacetic acid derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-11-15 | — | — | CN | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |