Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 11/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625506 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1TBXA2R | |
| SCHEMBL8625156 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8625004 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1TBXA2R | |
| SCHEMBL8627845 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8623913 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8627326 | 0.77 | MTNR1A (0.48) | KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL693383 | 0.76 | TDP1 (0.49) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL901768 | 0.75 | TDP1 (0.47) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8418748 | 0.75 | KMT2A (0.53) | KDM4EALDH1A1HPGDTDP1L3MBTL1 | |
| SCHEMBL8417285 | 0.75 | KMT2A (0.53) | KDM4EALDH1A1HPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |