Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10473850 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL11132340 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL11130015 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL10674145 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL11130012 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL10564270 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL8622094 | 0.79 | MEN1 (0.38) | ALDH1A1MEN1KMT2ACCKBRGAA | |
| SCHEMBL8077395 | 0.78 | KMT2A (0.38) | ALDH1A1MEN1KMT2ALMNACACNA2D1 | |
| SCHEMBL8082394 | 0.78 | CHRM1 (0.36) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL11218592 | 0.78 | MEN1 (0.52) | ALDH1A1MEN1KMT2ACCKBRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503597-B1 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KK (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5599925-A | BACTERICIDES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-02-04 | — | — | US | disclosed |
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0503597-A2 | Penam derivatives and processes for producing the same | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1992-09-16 | — | — | EP | disclosed |
| EP-0344197-B1 | NOVEL N-1 SUBSTITUTED BETA-LACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1991-08-14 | — | — | EP | disclosed |
| US-5015737-A | Antibiotics, bactericides | THE UPJOHN COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| US-5006650-A | Antibiocides | THE UPJOHN COMPANY (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0368908-A1 | THERAPEUTICALLY USEFUL $g(b)-LACTAMS | THE UPJOHN COMPANY (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0352269-A1 | ANTIBIOTIC SULFONYLAMINOCARBONYL ACTIVATED $g(b)-LACTAMS | THE UPJOHN COMPANY (US) | 1990-01-31 | — | — | EP | disclosed |
| EP-0344197-A1 | NOVEL N-1 SUBSTITUTED BETA-LACTAMS AS ANTIBIOTICS. | UPJOHN CO (US) | 1989-12-06 | — | — | EP | disclosed |
| US-4883869-A | BACTERICIDES, ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1989-11-28 | — | — | US | disclosed |
| US-4837318-A | Carbonate substituted monobactams as antibiotics | THE UPJOHN COMPANY (US) | 1989-06-06 | — | — | US | disclosed |
| WO-1989000569-A1 | THERAPEUTICALLY USEFUL beta-LACTAMS | THE UPJOHN COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0300636-A1 | Therapeutically useful beta-lactams | THE UPJOHN COMPANY (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0281289-A1 | Antibiotic sulfonylaminocarbonyl activated beta-lactams | THE UPJOHN COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |
| WO-1988006588-A1 | ANTIBIOTIC SULFONYLAMINOCARBONYL ACTIVATED beta-LACTAMS | THE UPJOHN COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |
| WO-1988006156-A1 | NOVEL N-1 SUBSTITUTED beta-LACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1988-08-25 | — | — | WO | disclosed |
| EP-0221954-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1987-05-20 | — | — | EP | disclosed |
| WO-1986006722-A1 | CARBONATE SUBSTITUTED MONOBACTAMS AS ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1986-11-20 | — | — | WO | disclosed |