SCHEMBL8623707

SCHEMBL8623707

CS(=O)(=O)c1cc(-c2ccccn2)nc(-c2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.55
CCR5 P51681 3/20 0.55
CCR8 P51685 3/20 0.55
GPR39 O43194 2/20 0.54
CBFB Q13951 1/20 0.54
KDM4E B2RXH2 5/20 0.53
LMNA P02545 3/20 0.53
TP53 P04637 2/20 0.53
ALOX15 P16050 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ALPL P05186 1/20 0.53
HSP90AA1 P07900 1/20 0.53
ALPI P09923 1/20 0.53
ALPG P10696 1/20 0.53
MAPK1 P28482 1/20 0.53
CYP1A2 P05177 1/20 0.50
POLB P06746 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9677009 0.89 CCR1 (0.51) CCR1CCR5CCR8GPR39CBFB
SCHEMBL8512817 0.85 GPR39 (0.49) CCR1CCR5CCR8GPR39CBFB
SCHEMBL8512862 0.85 GPR39 (0.46) CCR1CCR5CCR8GPR39CBFB
SCHEMBL15402037 0.84 KDM4A (0.46) CCR1CCR5CCR8GPR39CBFB
SCHEMBL28004660 0.79 PTGS2 (0.51) CCR1CCR5CCR8GPR39CBFB
Dipyridyl SCHEMBL27645628 0.77 KDM4E (0.64) CCR1CCR5CCR8KDM4ELMNA
SCHEMBL8229590 0.76 PTGS2 (0.64) CBFBCYP1A2SCDPTGS2PTGS1
SCHEMBL310089 0.76 PTGS2 (0.49) GPR39CBFBSCDKDM4AKDM4B
Dipyridyl SCHEMBL7570387 0.75 KDM4E (0.61) CCR1CCR5CCR8CBFBKDM4E
SCHEMBL1104803 0.75 CCR1 (0.64) CCR1CCR5CCR8CBFBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1207272-A None JP disclosed
JP-2076853-A None JP disclosed
JP-1207271-A None JP disclosed
EP-0576036-B1 Optical information recording element using AZO dyes EASTMAN KODAK CO (US) 1998-05-20 EP disclosed
EP-0576036-A2 Optical information recording element using AZO dyes EASTMAN KODAK COMPANY (US) 1993-12-29 EP disclosed
US-5272047-A Optical information recording medium using azo dyes EASTMAN KODAK COMPANY (US) 1993-12-21 US disclosed
US-5104988-A Colorfast metallized dyes FUJI PHOTO FILM CO., LTD. (JP) 1992-04-14 US disclosed
US-4960895-A AS A LIGAND FOR MAKING METALLIZED DYES FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 US disclosed
JP-H0276853-A 4'-ALKOXY-2,2':6,2\"-TERPYRIDINE DERIVATIVE AND METAL COMPLEX THEREOF FUJI PHOTO FILM CO LTD 1990-03-16 JP disclosed
JP-H01207271-A PRODUCTION OF 4-HYDROXYOLIGOPYRIDINES FUJI PHOTO FILM CO LTD 1989-08-21 JP disclosed
JP-H01207272-A PRODUCTION OF 4-HYDROXYOLIGOPYRIDINES FUJI PHOTO FILM CO LTD 1989-08-21 JP disclosed
EP-0187984-B1 POLYMERIC MORDANT CONTAINING NITROGEN-COORDINATING LIGAND FOR METALLIZABLE DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-11-09 EP disclosed
EP-0187340-B1 PHOTOGRAPHIC PRODUCTS EMPLOYING NOVEL NONDIFFUSIBLE METAL COMPLEXES OF AZO DYES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-09-21 EP disclosed
EP-0187984-A1 Polymeric mordant containing nitrogen-coordinating ligand for metallizable dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-23 EP disclosed
EP-0187340-A1 Photographic products employing novel nondiffusible metal complexes of AZO dyes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-07-16 EP disclosed
US-4599389-A COLOR PHOTOGRAPHY DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1986-07-08 US disclosed
US-4598030-A Photographic products employing novel nondiffusible metal complexes of azo dyes EASTMAN KODAK COMPANY (US) 1986-07-01 US disclosed
US-4581314-A FOR COLOR DIFFUSION TRANSFER PHOTOGRAPHY; RAPID DYE METALLIZATION EASTMAN KODAK COMPANY (US) 1986-04-08 US disclosed