Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555208 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDGAARAB9A | |
| SCHEMBL11517533 | 0.83 | PRSS1 (0.60) | ALDH1A1MAPTHPGDPRSS1TPSAB1 | |
| SCHEMBL16207467 | 0.82 | ABCB1 (0.50) | ALDH1A1MAPTHPGDKMT2ASMN1; SMN2 | |
| SCHEMBL84134 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDRAB9AKMT2A | |
| SCHEMBL28459939 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTHPGDKMT2AGLA | |
| SCHEMBL11790891 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTHPGDRAB9AKMT2A | |
| SCHEMBL1782358 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDRAB9AKMT2A | |
| SCHEMBL7350797 | 0.79 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDRAB9AKMT2A | |
| SCHEMBL3084308 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDKMT2AGLA | |
| SCHEMBL8620509 | 0.78 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |