Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505433 | 0.87 | PRSS1 (0.59) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL25380156 | 0.86 | PRSS1 (0.57) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL8426730 | 0.85 | PRSS1 (0.56) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL8571304 | 0.85 | PRSS1 (0.63) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| Hydrochloric Acid SCHEMBL9116244 | 0.84 | PRSS1 (0.62) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL8623733 | 0.83 | ALDH1A1 (0.45) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| SCHEMBL7146925 | 0.83 | PRSS1 (0.71) | PRSS1TPSAB1ALDH1A1HPGDABCB1 | |
| SCHEMBL7136752 | 0.83 | PRSS1 (0.71) | PRSS1TPSAB1ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL8852576 | 0.83 | PRSS1 (0.60) | PRSS1TPSAB1ALDH1A1CACNA1HMAPT | |
| SCHEMBL8241799 | 0.82 | CACNA1H (0.56) | PRSS1TPSAB1ALDH1A1CACNA1HABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |