Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623927 | 1.00 | MEN1 (0.59) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL10873562 | 0.84 | MEN1 (0.51) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL10876148 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL10876160 | 0.83 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL10874257 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL10874264 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL1313381 | 0.81 | EPHX2 (0.52) | KMT2AMAPTRAB9ANPC1MAOA | |
| SCHEMBL1313384 | 0.81 | EPHX2 (0.52) | KMT2AMAPTRAB9ANPC1MAOA | |
| SCHEMBL6251503 | 0.81 | EPHX2 (0.52) | KMT2AMAPTRAB9ANPC1MAOA | |
| SCHEMBL10873724 | 0.81 | GPR35 (0.44) | MAPTALDH1A1KCNK3KCNK9GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684942-B1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORP (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5488111-A | 8-sulfo-3-quinoline carboxylic acid compounds | HOECHST CELANESE CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| EP-0684942-A4 | — | — | 1995-12-27 | — | — | EP | disclosed |
| EP-0684942-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1995-12-06 | — | — | EP | disclosed |
| US-5466808-A | 8-sulfo-3-quinoline carboxylic acids and process therefore | HOECHST CELANESE CORPORATION (US) | 1995-11-14 | — | — | US | disclosed |
| US-5430152-A | Heating aminoarylester in presence of chlorosulfonic acid, oleum | HOECHST CELANESE CORPORATION (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1994019312-A1 | METHOD FOR PREPARING QUINOLINE CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | HOECHST CELANESE CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |