Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 4/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624405 | 0.92 | NSD2 (0.60) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8604566 | 0.85 | NSD2 (0.59) | ALDH1A1KDM4ETDP1FABP4NSD2 | |
| SCHEMBL8627845 | 0.78 | KDM4E (0.50) | ALDH1A1KDM4ETDP1FABP4HPGD | |
| SCHEMBL29508099 | 0.76 | CYP3A4 (1.00) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL317956 | 0.76 | CYP3A4 (1.00) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL17383734 | 0.75 | CYP3A4 (0.68) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14919628 | 0.75 | NSD2 (0.83) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11372267 | 0.74 | TBXA2R (0.69) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8625506 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4ETDP1HPGDTBXA2R | |
| SCHEMBL8625004 | 0.73 | KDM4E (0.50) | ALDH1A1KDM4ETDP1HPGDTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |