Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 8/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.45 |
| ▸ | FABP4 | P15090 | 5/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604566 | 0.83 | NSD2 (0.59) | KDM4EALDH1A1HPGDTDP1FABP4 | |
| SCHEMBL8624405 | 0.81 | NSD2 (0.60) | KDM4EALDH1A1HPGDTDP1TBXA2R | |
| SCHEMBL8624608 | 0.80 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8623938 | 0.78 | ALDH1A1 (0.61) | KDM4EALDH1A1HPGDTDP1TBXA2R | |
| SCHEMBL8625156 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8602989 | 0.73 | PTGIR (0.42) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL9512068 | 0.73 | TBXA2R (0.63) | ALDH1A1TDP1TBXA2R | |
| SCHEMBL8420341 | 0.72 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| SCHEMBL8623913 | 0.70 | KDM4E (0.46) | KDM4EALDH1A1HPGDTDP1PTGIR | |
| Naphthyloxyacetic Acid SCHEMBL6820182 | 0.70 | KDM4E (0.96) | KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | claimed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | claimed |
| EP-0657422-B1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5624959-A | INHIBITING UTERINE CONTRACTIONS, PROSTAGLANDIN ANTAGONIST OR AGONIST, ANALGESICS AND ANTISECRETORY AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0657422-A1 | Naphthyloxyacetic acid derivatives as PGE2 agonists and antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |