Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623899 | 0.91 | TDP1 (0.39) | PTGDR2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8621962 | 0.90 | PTGDR2 (0.44) | PTGDR2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8618263 | 0.84 | ANO1 (0.46) | PTGDR2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8620586 | 0.83 | FFAR1 (0.42) | MEN1KMT2ASMN1; SMN2POLBKDM4E | |
| SCHEMBL8617286 | 0.83 | PTGDR2 (0.46) | PTGDR2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8622048 | 0.80 | TDP1 (0.41) | PTGDR2TSHRKMT2AALDH1A1MAPT | |
| SCHEMBL8620524 | 0.77 | HIF1A (0.48) | ALDH1A1L3MBTL1PPARGPPARAHTT | |
| SCHEMBL27294425 | 0.75 | SMN1; SMN2 (0.45) | PTGDR2TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8620478 | 0.75 | MRGPRX4 (0.43) | PTGDR2TSHRSMN1; SMN2NPC1MAPT | |
| SCHEMBL8623430 | 0.73 | ANO1 (0.48) | PTGDR2MAPTCYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |