Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 4/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623430 | 0.90 | ANO1 (0.48) | ANO1PTGDR2ANO2MAPTFFAR4 | |
| SCHEMBL8623899 | 0.89 | TDP1 (0.39) | PTGDR2MAPTFFAR4KDM4EMEN1 | |
| SCHEMBL8623949 | 0.84 | PTGDR2 (0.41) | PTGDR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8622051 | 0.84 | ANO1 (0.50) | ANO1PTGDR2ANO2MAPTFFAR4 | |
| SCHEMBL8620586 | 0.81 | FFAR1 (0.42) | FFAR1KDM4EMEN1KMT2AHIF1A | |
| SCHEMBL8622048 | 0.78 | TDP1 (0.41) | PTGDR2MAPTFFAR4KMT2AALDH1A1 | |
| SCHEMBL8620524 | 0.76 | HIF1A (0.48) | MRGPRX4ALDH1A1HIF1A | |
| SCHEMBL8618547 | 0.74 | MRGPRX4 (0.54) | PTGDR2MAPTMRGPRX4 | |
| SCHEMBL8621962 | 0.74 | PTGDR2 (0.44) | PTGDR2MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8620478 | 0.73 | MRGPRX4 (0.43) | ANO1PTGDR2MAPTFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |