Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8623949 | 0.91 | PTGDR2 (0.41) | TDP1MAPTPTGDR2ALDH1A1CYP1A2 | |
| SCHEMBL8618263 | 0.89 | ANO1 (0.46) | MAPTPTGDR2FFAR4ALDH1A1CYP1A2 | |
| SCHEMBL8622048 | 0.89 | TDP1 (0.41) | TDP1MAPTRXRARXRBRXRG | |
| SCHEMBL8620586 | 0.88 | FFAR1 (0.42) | RECQLPOLBKDM4EMEN1KMT2A | |
| SCHEMBL8617222 | 0.81 | CDK4 (0.44) | TDP1MAPTRXRARXRBRXRG | |
| SCHEMBL8621962 | 0.79 | PTGDR2 (0.44) | TDP1MAPTPTGDR2ALDH1A1POLB | |
| SCHEMBL8620524 | 0.79 | HIF1A (0.48) | ALDH1A1 | |
| SCHEMBL6058430 | 0.78 | MAPT (0.47) | TDP1MAPTRXRARXRBRXRG | |
| SCHEMBL8623430 | 0.78 | ANO1 (0.48) | MAPTPTGDR2FFAR4CYP1A2 | |
| SCHEMBL28864441 | 0.77 | RXRA (0.48) | TDP1RXRARXRBRXRGRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658541-B1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO (JP) | 1998-05-20 | — | — | EP | disclosed |
| US-5510506-A | Process for producing carboxylic acid derivatives | SHIONOGI & CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0658541-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |