Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SGK1 | O00141 | 1/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11379519 | 0.87 | AXL (0.60) | AXLKDM4EPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13824904 | 0.84 | ALDH1A1 (0.53) | KDM4EMAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7093171 | 0.83 | AXL (0.60) | AXLKDM4ESGK1CAMKK2MAPT | |
| SCHEMBL10561251 | 0.82 | AKR1C2 (0.53) | LMNASMN1; SMN2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL2490163 | 0.82 | CFTR (0.48) | AXLKDM4EMAPTKMT2ALMNA | |
| SCHEMBL3713695 | 0.82 | AXL (0.59) | AXLSGK1CAMKK2MAPTMEN1 | |
| SCHEMBL4876885 | 0.82 | AXL (0.59) | AXLSGK1CAMKK2MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7093169 | 0.82 | AXL (0.59) | AXLKDM4ESGK1CAMKK2MAPT | |
| SCHEMBL4910427 | 0.81 | PDGFRB (0.49) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL1854140 | 0.81 | MKNK1 (0.43) | AXLNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. | 2023-05-04 | — | — | US | disclosed |
| EP-0846684-A2 | Process for producing 2-halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5493028-A | Processes for producing 2-Halo-nicotinic acid derivatives and precursors thereto | REILLY INDUSTRIES, INC. (US) | 1996-02-20 | — | — | US | disclosed |
| EP-0633880-A1 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1993018005-A2 | PROCESSES FOR PRODUCING 2-HALO-NICOTINIC ACID DERIVATIVES AND PRECURSORS THERETO | REILLY INDUSTRIES, INC. (US) | 1993-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230134932-A1 | EIF4E INHIBITORS AND USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | AXL 3024/4885KDM4E 710/4885SGK1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.