Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8624004 | 1.00 | CTSK (0.44) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL4633702 | 0.86 | CTSK (0.47) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL5497072 | 0.86 | CTSK (0.47) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL7418023 | 0.86 | CTSK (0.47) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL8622116 | 0.85 | SLC1A3 (0.50) | CTSKCTSSCTSBCTSLSLC1A3 | |
| SCHEMBL8622114 | 0.85 | SLC1A3 (0.50) | CTSKCTSSCTSBCTSLSLC1A3 | |
| SCHEMBL9327711 | 0.84 | CTSK (0.48) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL7331165 | 0.84 | POLB (0.46) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL6622988 | 0.84 | POLB (0.46) | CTSKPOLBGAAMAPTXBP1 | |
| SCHEMBL5187344 | 0.83 | CTSK (0.47) | CTSKPOLBGAAMAPTXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |