Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 7/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622114 | 1.00 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL6946515 | 0.90 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL6946518 | 0.90 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL8624004 | 0.85 | CTSK (0.44) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL8624003 | 0.85 | CTSK (0.44) | SLC1A3SLC1A2SLC1A1MEN1CYP1A2 | |
| SCHEMBL6654265 | 0.84 | ALDH1A1 (0.50) | KMT2ACTSKCTSSCTSBALDH1A1 | |
| SCHEMBL9807069 | 0.84 | ALDH1A1 (0.50) | KMT2ACTSKCTSSCTSBALDH1A1 | |
| SCHEMBL9807067 | 0.84 | ALDH1A1 (0.50) | KMT2ACTSKCTSSCTSBALDH1A1 | |
| SCHEMBL9327734 | 0.84 | ALDH1A1 (0.50) | KMT2ACTSKCTSSCTSBALDH1A1 | |
| SCHEMBL4634087 | 0.84 | ALDH1A1 (0.50) | KMT2ACTSKCTSSCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712838-B1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD (JP) | 1998-11-04 | — | — | EP | disclosed |
| US-5795891-A | RHEUMATOID ARTHRITIS, OSTEOPOROSIS, HYPERCALCEMIA | KANEBO LTD. (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0848957-A1 | Fas LIGAND SOLUBILIZATION INHIBITOR | KANEBO LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |
| EP-0712838-A1 | ACYLPHENYLGLYCINE DERIVATIVE AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY INCREASED COLLAGENASE ACTIVITY CONTAINING SAID COMPOUND AS ACTIVE INGREDIENT | KANEBO LTD. (JP) | 1996-05-22 | — | — | EP | disclosed |