Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879327 | 0.86 | ERN1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL30138984 | 0.81 | ERN1 (0.56) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL16495093 | 0.80 | ERN1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL12672585 | 0.79 | ALDH1A1 (0.70) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL29957021 | 0.79 | ALDH1A1 (0.70) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL6763816 | 0.79 | ERN1 (0.49) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL16494291 | 0.77 | ERN1 (0.47) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL11071247 | 0.76 | ERN1 (0.46) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL4438653 | 0.76 | ERN1 (0.50) | ERN1ALDH1A1TRIM24TYRTRIM33 | |
| SCHEMBL2505574 | 0.76 | ERN1 (0.63) | ERN1ALDH1A1TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10045706-A | — | — | None | — | — | JP | disclosed |
| US-7393652-B2 | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-07-01 | — | — | US | disclosed |
| JP-H1045706-A | MEW DISULFIDE COMPOUND, PRODUCTION THEREOF AND PRODUCTION OF THIAZEPINE DERIVATIVE BY USING THE SAME COMPOUND | SUMITOMO SEIKA CHEM CO LTD | 1998-02-17 | — | — | JP | disclosed |