Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899409 | 0.89 | PDE4D (0.49) | STING1LMNANT5EADORA3ADORA2A | |
| SCHEMBL12352439 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL12595500 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL8624094 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL17772331 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL12729578 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL12222444 | 0.85 | STING1 (0.52) | AHCYSTING1ADORA3ADORA2AADORA2B | |
| SCHEMBL10719650 | 0.85 | ADORA3 (0.37) | STING1LMNANT5EADORA3PNP | |
| SCHEMBL8668421 | 0.83 | NT5E (0.36) | STING1LMNANT5EPNPTP53 | |
| SCHEMBL8594450 | 0.82 | AHCY (0.50) | AHCYSTING1LMNANT5EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6175004-B1 | REACTING AN OLIGONUCLEOTIDE COMPRISING A HALOGENATED PURINE NUCLEOSIDE WITH AMINE; FOR STRONGER HYBRIDIZATION; DIAGNOSIS; GENETIC ENGINEERING; ANTISENSE AGENTS | ISIS PHARMACEUTICALS, INC. | 2001-01-16 | — | — | US | disclosed |